Morphologi 4 provides detailed morphological descriptions of particulate samples through static image analysis, enabling a greater understanding of both sample and process. It can equally be used as an R&D tool to investigate challenging applications and in automated QC analysis where generation of robust, user-independent results and validation are required. The Morphologi 4 measures the particle size and shape of dry powders, wet suspensions and particulates on filters. Designed to accommodate the diverse needs of a multidisciplinary R&D lab, it is the ideal replacement for costly and time-consuming manual microscopy.

The Morphologi 4 measurement procedure can be split into four sections:

Sample preparation:

Spatial separation of individual particles and agglomerates is critical to representative results. The integrated dry powder disperser makes preparing dry powder samples easy and reproducible.

Image capture:

The instrument captures images of individual particles by scanning the sample underneath the microscope optics.The Morphologi 4 can illuminate the sample from below or above, whilst accurately controlling the light levels.

Image processing:

Use of either the automated ‘Sharp Edge’ segmentation analysis or the manually-controlled thresholding enables the detection of particles and the calculation of a range of morphological properties for each.

Results generation:

Statistically representative distributions are constructed for each parameter from the thousands of particles that have been analyzed. Advanced graphing and data classification options in the software ensure that extracting the relevant data from the measurement is straightforward, via an intuitive visual interface. Individually-stored grayscale images for each particle provide qualitative verification of the quantitative results.