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Upright microscopes for life science research

Get the publication-quality imaging and customizable upright microscope solution you need for your Life Science research with Leica Microsystems. These powerful imaging systems feature constant color, natural light illumination, superior optics, and configurable options to provide high contrast, brilliant images for your cutting-edge biological research.

Upright microscopes for industrial and materials

Get insights into the smallest details and inspect and document results efficiently with industrial and materials upright microscopes from Leica Microsystems. Each solution can be customized with brilliant, cool LED illumination, ergonomic accessories, sophisticated digital cameras and intuitive software to meet a broad range of applications.

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Available models

Upright Microscopes for PolarizationLeica DM4 P, DM2700 P & DM750 P

If you would like to investigate crystalline structures, polarization microscopy will serve you best. Whether it be minerals, plastics and polymers, drugs and pharmaceuticals, or pigments and cement, with our polarization microscopes you will see what interests you most as a researcher or in quality assurance.

Depending on your application, you can choose from three different systems for polarization microscopy:

  • The fully coded and semi-automated Leica DM4 P
  • The manual Leica DM2700 P
  • The Leica DM750 P educational microscope

THUNDER Imager Tissue

The THUNDER Imager Tissue allows real-time fluorescent imaging of 3D tissue sections typically used in neuroscience and histology research. Acquire rich, detailed images of thick tissues free of haze from out-of-focus blur.

Even fine structures deep in tissues can be resolved thanks to Computational Clearing, an innovative Leica technology. Image detailed morphological structures like axons and dendrites of neurons in a brain slice. The high image quality, even with thick tissue sections, is combined with the well-known speed, fluorescence efficiency, and ease of use of widefield microscopes.

Gain these advantages using a THUNDER Imager Tissue for your research:

  • Rapidly acquire blur-free images showing finest details of the morphology, even deep within thick sections
  • Get fast overviews of whole tissue sections
  • Image and analyze challenging tissue sections with an easy workflow

Microstructure Composition Analysis Solution DM6 M LIBSMicrostructure Composition Analysis Solution DM6 M LIBS

Combine visual and qualitative chemical inspection in a single work step and save 90% of your time to determine microstructure composition compared to inspection with conventional SEM/EDS. Integrated Laser Induced Breakdown Spectroscopy (LIBS) delivers the exact chemical fingerprint of the material’s structure that you see in the microscope image - within a second.

  • 2 systems in 1 for visual & chemical analysis
  • 1 second to a chemical fingerprint
  • 0 sample preparation

Done!

Examine exactly what you see via the eyepieces or camera with a single click for fast and simple identification and interpretation. No additional expertise by the operator is required. 

Upright Microscopes Leica DM4 B & DM6 B

Increase your work efficiency with the Leica DM4 B or Leica DM6 B upright digital research microscopes! Both are ideally suited to making your work life easier in biomedical research and clinical labs alike.

  • Simplify your workflow with automated functions and easy-to-use software
  • Easily capture publication-quality images by utilizing the 19-mm sCMOS camera imaging port
  • Create fast overviews of your samples and identify the important details instantly with the LAS X Navigator Software
  • Have great flexibility through the choice of accessories such as Halogen or LED illumination

Optical microscopes Leica DM2500 & DM2500 LED

Leica DM2500 & DM2500 LED optical microscopes are tools for demanding tasks in life science routine and research applications. With their transmitted light illumination, optical performance, and state-of-the-art accessories, they are especially well-suited for challenging life science research tasks that require differential interference contrast or high-performance fluorescence.

The difference between the two optical microscopes is their illumination: DM2500 LED is equipped with LED illumination for transmitted light, DM2500 works with halogen. Both types of illumination render a realistic impression of the colors of the sample, so that users in clinical applications, such as the frequently used HE specimen staining, are able to assess the colors of their samples accurately.

Designed with application-oriented modularity, the DM2500 & DM2500 LED can be configured to fit a wide variety of applications and accommodate the diverse physical requirements of individual users.

Ergonomic system microscope Leica DM1000 LED

The Leica DM1000 LED features long-life LED illumination that provides near daylight, bright illumination with constant color temperature and emits less heat.

The LED also eliminates the need for lamp changes, which saves time and money. Because of its low power consumption, the system is energy efficient. Users of the Leica DM1000 LED benefit from the system’s ability to uniquely adapt to every user.

It is ideal for all clinical laboratory applications, especially for cytology, haematology, and pathology. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF).

Leica Microsystems also offers a portable, battery-powered option for field use.

The Inspection System for Microelectronics and Semiconductor DM3 XL

Speed matters in inspection, process control, or defect and failure analysis for the microelectronics and semiconductor industry. The faster you detect a defect, the faster you can react.

30% more field of view

With a large field of view, the DM3 XL inspection system allows your team to identify defects faster and increase your yield rate. Make use of the 30% increased field of view of the unique macro objective.

3D Optical Surface Metrology System Leica DCM8

Designed to help you maximize efficiency, Leica DCM8 unites the advantages of High Definition confocal microscopy with interferometry into one versatile, dual-core system. Ultra-fast analysis is ensured thanks to one-click mode selection, sophisticated software and HD confocal scanning without moving parts.

Uniquely Ergonomic System Microscope Leica DM1000

The ergonomically designed Leica DM1000 with adjustable features and easy-to-use controls adapts to every user to improve comfort and convenience while working at the microscope.

Featuring high-quality optical performance, the Leica DM1000 is ideal for all clinical laboratory applications, in particular cytology, haematology, and pathology. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF).

Its advanced capabilities, including fluorescence, make it well suited also for complex tasks.

Ergonomic System Microscopes for Complex Clinical Applications Leica DM2000 & DM2000 LED

With their sophisticated modular design and high-performance fluorescence, the Leica DM2000 microscopes are ideal for complex tasks in pathology, cytology, and many other applications. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF).

The Leica DM2000 microscopes can be configured with a variety of optics and contrast techniques to meet the specific requirements of demanding applications.

Leica DM2000 is available in two versions, with bright halogen illumination, or with long-life LED.

Upright Materials Microscopes Leica DM4 M & DM6 M

Do you need to image, measure, and analyze similar features across many samples and materials science and analysis? The Leica DM4 M and Leica DM6 M are the Industrial Microscopes for you, whether microscopy novice or professional.

  • Use the Leica DM4 M for manual routine inspection
  • Use the Leica DM6 M for fully automated materials analysis

You can easily recall previous microscope settings and instantly reproduce imaging parameters with the unique Store and Recall software functions. For every sample type.

One-button Intelligent Automation makes your repetitive work easy. Reduce training time, improve your workflow, and get brilliant imaging results every time with the microscopes that don’t forget.

Fixed Stage Microscope Leica DM6 FS

Do you work in a field such as electrophysiology, evolutionary biology, or neuroscience where outstanding stability is required for successful experiments? The Leica DM6 FS fixed stage fluorescence microscope is an ideal instrument for your present and future challenges!

  • Confidently perform your experiment with the highest degree of mechanical and electronic stability
  • Save time using the microscope’s full range of automated functions
  • Efficiently work with tools and accessories using special Leica optics that provide ample clearance around the specimen
  • Add special techniques based on the Leica DM6 FS for Optogenetics and Cryo CLEM

Upright Materials Microscope Leica DM2700 M

This materials microscope combines high-quality Leica optics with state-of-the-art universal white light LED illumination. It is an ideal inspection tool for all kinds of routine inspection tasks in metallography, earth science, forensic investigation, and materials quality control and research. The Leica DM2700 M shows you how simple and reliable microscopy can be while helping to improve workflow.

Forensic Comparison Microscope with LED Illumination Leica FS4000 LED

The Leica FS4000 LED forensic comparison microscope combines the latest light microscopy technology with unequalled user friendliness and ergonomy in an integrated solution.

The Leica FS4000 LED enables high precision comparison of two objects at magnifications up to 1500x and supplies reliable evidence of the tiniest differences between the microstructure, texture, and color of samples. Contrast techniques such as brightfield, fluorescence, and polarization are provided, and the user can select a contrast mode in a fraction of a second. Various imaging modes (split, superimposed, and combined image) can be set with the press of a button.

Materials Analysis Microscope Leica DM1750 M

With a focus on tasks in the material lab or research

The new Leica DM1750 M is a material microscope designed for rapid, accurate analysis results even for a use in rough ambient conditions.

Working with the Leica DM1750 M you will see, how simple and reliable microscopy can be. Its robust design contains an excellent optical system and allows the inspection even of larger samples, in brightfield, oblique- or with polarized light. The entire reflected light illumination is carried out with Power-LEDs which allow an inspection with different illumination angles, especially suitable for the detection of micro scratches or for gaining height information.

High Throughput 8" Inspection & Review System Leica DM8000 M

New optical features offered by the Leica DM8000 M such as the optional macro mode or the oblique UV illumination (OUV, with i-line UV option) not only improve resolving power but also speed up throughput when inspecting samples with 8’’/200 mm diameter.

The illumination is based on the latest LED technology and is fully integrated into  the microscope. The low heat radiation and integration into the stand ensures that there is an optimal airflowaround the microscope. The long lifetime yet extremely low power consumption of the LEDs offer enormous savings potential.

With a single touch of a button you can change the magnification, the illumination or contrast mode.

Precision 12" Inspection & Review System Leica DM12000 M

Optical features offered by the Leica DM12000 M such as the optional macro mode or the oblique UV illumination (OUV, with i-line UV option) not only improve resolving power but also speed up throughput when inspecting samples with 12’’/300 mm diameter.

The illumination is based on the latest LED technology and is fully integrated into the microscope. The low heat radiation and integration into the stand ensures that there is an optimal airflowaround the microscope. The long lifetime yet extremely low power consumption of the LEDs offer enormous savings potential.

With a single touch of a button you can change the magnification, the illumination or contrast mode.

Compound Microscope Leitz Optilux

Leitz Optilux is a proud member of the Leica Microsystems family of microscopes and offers the ultimate in comfort and quality at a reasonable price.

It is ideal for viewing prepared microscope slides in brightfield for studying microstructures not visible with the human eye.

Monocular, binocular or trinocular educational microscope for life science courses Leica DM300

For slightly more advanced students in biology or 2-4 year college life science classrooms, the Leica DM300 compound microscope is compact, maintenance-free and easy to use to provide trouble free operation each day.

Equipped with a mechanical stage to accommodate two specimen slides and labelled Abbe condenser, the DM300 can be configured with rotatable monocular or binocular tubes for shared viewing and easy storage. Trinocular tube is also possible to go digital.

With 165 years of microscope design and manufacturing experience, the Leica DM300 student microscope provides students with the capabilities they need to study the finest details in all the Life Sciences.

Binocular, fluorescence-capable educational microscope for life science courses Leica DM500

The Leica DM500 microscope with “plug and play” capability is the ideal tool to make teaching entry-level college and university Life Science courses easy and fun for the instructor and the student.

Student-friendly features such as the pre-focused, pre-centered condenser and the EZTube™ preset diopter, which prevent incorrect adjustments, provide more time for hands-on teaching.

EZStore™ design with integrated handle and cord wrap allows easy carrying, easy lifting and protection against microscope component damage. 

Binocular, fluorescence-capable microscope for postdocs in the life sciences Leica DM750

The Leica DM750 is the ideal microscope for the versatile needs of advanced college and university life science courses and professional training in medical, veterinary and dental schools.

The student-friendly features such as the EZStore™, which provides easy carrying and easy lifting and EZGuide with rounded edges, which allows one-handed slide loading and reduces slide chipping provide a safer classroom environment.

The teacher-friendly features, such as the EZLite™, which provides over 20 years of LED illumination and automatic time delay shutoff, saves time and energy.

Binocular materials microscope for education and metallography Leica DM750 M

The Leica DM750 M is the ideal microscope for basic materials applications in an Industrial Lab or Material Science course. Its versatile stage and reflected light system work in combination to deliver high quality images of the most demanding specimens.

The mechanical stage can be used for both transmitted and reflected light. It can be equipped with various specimen holders to accommodate mounted specimens of different diameters.

The unique Reflected light LED illuminator provides brightfield, polarized light, and oblique illumination. This allows you to work with many different specimens with the same microscope configuration.

Fluorescence Microscope System for Advanced Imaging and Analysis LAS X Widefield Systems

The LAS X Widefield Systems are ideal for applications in fluorescence microscopy and image analysis including live cell time-lapse experiments, multi-positioning, z-stacking and deconvolution.

The versatile, fully integrated solutions offer harmony between hardware and software and combine the ultimate speed, reliability, and facilities for experiment design, analysis, and operational convenience.

For highly demanding applications, the LAS X Widefield Systems offers high-speed acquisition, TIRF, Fura2, FRET SE, Screening, Ca2+and ratio imaging, and peripheral triggering.

Uniquely Ergonomic System Microscopes With Intelligent AutomationLeica DM3000 & DM3000 LED

Enhance Laboratory Workflow

The Leica DM3000 microscopes for pathology, cytology,haematology and many other applications feature a motorized nosepiece, condenser head, automated light intensity adjustment, and optional foot pedal. These intuitive microscopes improve workflows significantly. For special diagnostics requirements, the microscope is certified for in-vitro-diagnostics (IVD) like in-vitro-fertilization (IVF).

The motorized condenser head knows the correct position for each magnification. The Leica DM3000 automatically adjusts light intensity to each objective’s requirements, stores previously used light values for each magnification, and boosts efficiency when changing between two magnifications thanks to its unique toggle mode.

Motorized Forensic Comparison Microscope Leica FS CB

The Leica FS CB comprises a motorized comparison bridge that is configured with two Leica DM Series microscopes.

The bridge features a built-in ergonomic observation tube for maximum viewing comfort. Various imaging modes (split, superimposed, and combined image) are set at the press of a button.

The Leica FS CB is ideal for all microscopic investigations that require direct side-by-side, high-precision comparison of two objects at magnifications up to 1500x.

Motorized Forensic Comparison Macroscope Leica FS C

The modular Leica FS C motorized comparison macroscope is used for a wide range of forensic investigations including ballistics, toolmark, and document comparison. Intelligent Automation combines with outstanding ergonomic design.

The five apochromatically-corrected macro objectives feature a high numerical aperture and built-in, adjustable iris diaphragms for top optical performance.

Different imaging modes (split image, superimposed image and combined image) are set at the press of a button. This convenient platform provides increased reproducibility, accuracy, and efficiency.

Manual Forensic Comparison Macroscope Leica FS M

The Leica FS M manually-controlled forensic macroscope provides the flexibility, convenience, and comfort that make it the universal instrument of a firearms and toolmark examiner.

The versatile system is ideal for the simultaneous observation of evidence for training and consultation. The high-quality comparison bridge supports two precisely matched sets of apochromatically corrected objectives on quintuple ball-bearing nosepieces.

A 22mm field of view produces erect, unreversed images. The image moves in the same direction as the object for quick, easy manipulation.

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Leica Microsystems

Leica Microsystems develops and manufactures microscopes and scientific instruments for the analysis of microstructures and nanostructures..

Widely recognized for optical precision and innovative technology, the company is one of the market leaders in compound and stereo microscopy, digital microscopy, confocal laser scanning and super-resolution microscopy with related imaging systems, electron microscopy sample preparation, and surgical microscopy..

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