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Tangential Flow Filtration (TFF) Process Solutions
Spanning production capacity needs with maximum equipment utilization. Mitigate the risk of operator error and significantly reduce your development time in both single-use or hybrid processes. Our solutions provide high-performance from process development to commercial manufacturing in various upstream and downstream bioprocessing steps, including cell harvest, clarification, perfusion, ultrafiltration, and diafiltration.

Sartorius offers flexible tangential flow filtration (TFF) systems for process development and clinical trials, from laboratory environments up to commercial production batches. The TFF portfolio can flex to accommodate individual requirements, with a range of options that includes cost-efficient multi-use systems or closed systems with single-use flow kits for aseptic processing.


Key Features

• PD & Bench scale up to Pilot to Commercial scale
• Membrane area 10 cm² - 10 m²
• Ultrafiltration and Microfiltration cassettes
• Single use and Multiuse

Technical Specifications

Model Ambr® Crossflow Sartoflow® Smart Sartoflow® Advanced Sartoflow® 150 Sartoflow® Expert SU Sartoflow® 1000 Sartoflow® 4500
Membrane Area 10, 50 cm² 50 cm² - 0.14 m² 0.1 – 0.21 m² 0.1 – 0.4 m² 0.1 – 0.4, 1.4 m² 0.6 – 2.8 m² Up to 10 m²
Vessel Volume 100 mL 1 L with mixing 10 L 5, 10, 20 L 20 L mixing 10, 20, 100 L
Flow Rate / Pump Capacity 0 – 80 mL/min 1 – 100 L/h 700 L/h 5 – 150 L/h 900L/h 20 – 1,000 L/h 00 – 4500 L/h
Minimum Recirculation Volume 5 mL < 20 mL ~ 170 mL 130 mL ~ 600 mL ~ 1.2 L Depends on bag size
Automation Level Fully Semi Fully Fully Fully Fully
Process Mode (multi/single) Multi-use or single-use Multi-use Multi-use Single-use Single-use Single-use

Sartorius - Sartoflow® 150

Sartorius - Sartoflow® Expert SU

Sartorius - Sartoflow® 1000

Sartorius - Sartoflow® 4500

  • Pharmaceutical
  • Food & Beverage
Sartorius Lab InstrumentsThe Sartorius Group is a leading international partner of the biopharmaceutical industry and the research sector. We are helping biotech scientists and engineers across the entire globe to develop and manufacture medications from the first idea to production. So more people will have access to better medicine.
[Sartorius, Crossflow filtration, TFF, Tangential Flow Filtration, cell harvest, clarification, perfusion, ultrafiltration, diafiltration]