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Biotech

Innovation and research are the main drivers of the biotechnology and life sciences industry. Recent biotechnological and scientific advances are paving the way for more exciting novel biotechnological research, development and commercialization of new sustainable products. The field of biological manufacturing is faced with more complex molecules in development, changing capacity needs, uncertain forecasts and increased competition. Each new breakthrough or discovery involves complex diagnostic instruments, analytical instruments, testing equipment and many other specialized products that are utilized by personnel with the required expertise.

Getting these new products to market promptly can be a major challenge for many companies. At DKSH, we have experience in biotechnological and biophysical analysis and can provide the required knowledge and product support for these advanced scientific equipment.

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Measurement types

Particle size distribution

Particle size analysis in the range 0.01-3500 microns. For nanoparticle analysis see dedicated section.

Morphology

Morphological analysis of particles in the range 0.5-10000 microns (size, shape and transparency of particles). Integrated Raman chemical analysis with MDRS (Morphologically Directed Raman Spectroscopy).

Nanoparticle characterization

Size, concentration and zeta potential anlysis of nano-systems using light scattering techniques such as DLS, ELS and NTA techniques.

Rheology, Viscosity and Powder Flowability

Viscosity measurement and visco-elastic properties characterization of liquid dispersions, complex fluids and semi-solid materials.

Stability analysis

Rapid and objective quantification of concentrated dispersion real stability using Multiple Light Scattering.

High pressure homogenizer

High pressure homogenizing technique to produce stable nanoemulsions, reduce particle size or molecular weight of polysaccharides, nanoencapsulation, de-agglomeration, etc.

Exosomes and EVs characterization

Multiparametric characterization of exosomes and EVs including Sizing, Concentration per size range, Count, Phenotyping, Cargo, Integrity, Purity, etc.

Biomolecular interactions

Biomolecular interactions of proteins, antibodies, nucleic acids, lipids and other biomolecules using ITC Microcalorimetry or BioLayer Interferometry BLI techniques.

Protein aggregate analysis

SEC is the standard method for protein aggregate analysis. The choice of pore size is related to the size of the molecule to be separated.

Polymer characterization

Gel permeation chromatography (GPC) that separates analytes on the basis of size, typically in organic solvents. The technique is often used for the analysis of polymers.

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