Optimizing Mobile Phase Solvent Purity for LC-MS White paper

In the precise analysis of trace molecules, liquid chromatography mass spectrometry (LC-MS) plays a crucial role. It is critical that researchers upgrade from HPLC-grade solvents to LC-MS grade solvents designed specifically to meet the strict demands of modern LC-MS systems in order to enhance sensitivity and accuracy.

There are seven solvents that are being compared in this whitepaper across four LC-MS systems, accounting for factors such as baseline noise, UV impurities, signal intensity, contamination, and metal ion content. 

Download this whitepaper to discover how LC-MS-grade solvents can :

  • Reduce baseline noise and UV impurities
  • Improve signal intensity for target analytes
  • Outperform competitors in terms of contamination control to ensure reliable and reproducible chromatography