Label-Free Characterization of the Interleukin-6 Receptor and Anti-IL-6R Antibody Drug Tocilizumab using Alto Application note

Label-Free Characterization of the Interleukin-6 Receptor and Anti-IL-6R Antibody Drug Tocilizumab Using AltoTM Digital SPR

Therapeutic monoclonal antibodies are one of the fastest growing classes of drugs, and interleukins and their signal pathways are a preeminent target for treatments due to the vast number of problems their improper regulation present. Surface plasmon resonance (SPR) is a powerful tool that is well-suited for analyzing the binding interactions associated with signaling proteins, their receptors and related effectors.